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Vetra Stabil AQ | VetraSphere Aquaculture — Integria Care
VetraSphere Aquaculture

Vetra Stabil AQ

EHP and vibriosis control — broad-spectrum preventive health formulation for shrimp culture.
Prepared for: VetraSphere Aquaculture — Integria Care

"Preventive formulation for the control of EHP and vibriosis, growth improvement and consistent productivity in shrimp culture."

Product Description Composition
Aquaculture shrimp protection
180+ ac
Field Trials Across
6 Locations
5 days
Best Cases Improve
After Treatment
2.5 g/kg
Prevention Dose
per kg of Feed
5 g/kg
Treatment Dose
per kg of Feed

1. Product Description

What is
Vetra Stabil AQ?

A cutting-edge preventive solution that transforms the health of your ponds with broad-spectrum action. Combats EHP and vibriosis, strengthens the immune system and supports sustained productivity throughout the entire culture cycle.

EHP and vibriosis control — broad-spectrum preventive formulation
Immune function — supports and strengthens the immune system
Digestive performance — improves nutrient absorption and growth
Healthy environments — consistent productivity in the culture cycle

Sustained Productivity

Vetra Stabil AQ minimizes disease outbreaks and boosts digestive performance for a more resilient shrimp. It delivers healthier pond environments and consistent results throughout the entire culture cycle.

A cutting-edge preventive solution that transforms pond health with broad-spectrum action.
Shrimp aquaculture pond

Control and Prevention of EHP

"Combating EHP and vibriosis
from the source."

2. Core Features

A Resilient, Healthy and
Productive Shrimp Culture

Three core pillars define Vetra Stabil AQ — combating EHP and vibriosis, strengthening the immune system and sustaining productivity throughout the culture cycle.

Combats EHP and Vibriosis
  • Cutting-edge preventive solution
  • Transforms pond health
  • Broad-spectrum action
Strengthens the Immune System
  • Minimizes disease outbreaks
  • Boosts digestive performance
  • A more resilient shrimp
Sustained Productivity
  • Healthier pond environments
  • Consistent results
  • Throughout the entire culture cycle
EHP and Vibriosis Control
  • Broad-spectrum preventive health formulation
Immune Function
  • Supports and strengthens the shrimp's immune system
Digestive Performance
  • Improves nutrient absorption and growth
Healthy Environments
  • Consistent productivity during the culture cycle

3. Product Technology

CQNS™, BQNS™ & PQNS™

Carbon Quantum Nano Sphere, Botanical Quantum Nano Sphere and Phytosome Quantum Nano Sphere for the control of EHP and associated diseases. A quantum nano sphere technology product.

CQNS™ — Carbon Quantum Nano Sphere
Functional carbon nanostructures for cellular penetration and targeted action against pathogens.
BQNS™ — Botanical Quantum Nano Sphere
Plant-derived bioactive compounds with antimicrobial and anti-inflammatory properties.
PQNS™ — Phytosome Quantum Nano Sphere
Advanced delivery systems that improve the bioavailability and efficacy of the active compounds.

4. Disease Impact

Freedom from EHP
and Stunted Growth

EHP damages the gut and causes nutrient malabsorption and stunted growth. EHP spores can remain viable up to 6 months and retain infectivity for more than a year under aqueous conditions.

1

Enterocytozoon hepatopenaei (EHP)

Damaged gut, nutrient malabsorption and stunted growth. Gut damage and desquamation due to Vibrio PIR toxins; weak immune system and establishment of vibriosis infection.

2

Associated Effects

White Muscle Disease (WMD), White Feces Syndrome (WFS) and Soft Shell Syndrome. Found in slow-growing shrimp and shrimp with mortality associated with WFS.

V. harveyi V. splendidus V. parahaemolyticus V. alginolyticus V. anguillarum V. vulnificus V. campbellii V. fischeri V. damsela V. pelagicus V. orientalis V. ordalii V. logei

5. Benefits for Producers

Six Benefits
for Producers

Reduced disease risk, optimal FCR, better production, successful harvest, indirect cost benefit and total confidence for the shrimp producer.

01
Risk Reduction — reduces the risk of EHP disease and vibriosis.
02
Optimal FCR — no stunted growth, which keeps the FCR high.
03
Better Production — improves growth for better production.
04
Successful Harvest — normal growth continues and allows a successful harvest with a good count.
05
Cost Benefit — the cost benefit is indirect, as the producer harvests as in a normal cycle.
06
Total Confidence — confidence of having no losses due to EHP and vibriosis infections.

6. Field Trials

Validated Across More
Than 180 Acres

Field trials across more than 180 acres in 6 different locations on the south coast of India demonstrate the consistent performance of Vetra Stabil AQ.

Reduces WFS Risk
Reduces the risk of White Feces Syndrome and microsporidiosis.
Improvement in 5 Days
The best cases of ponds with stunted growth improve after five days of treatment and generate a good harvest.
Effective at Any Age
Effective at different animal ages (from day 7 to harvest).

Allows the producer to continue the culture with routine use of VETRA STABIL AQ.

7. Composition

Active Ingredients

A complete formulation built on nanoparticles, IgY antibodies (IQNS™), vitamins, chelated minerals, CQNS™-doped herbal actives, essential oils, organic acids, immunostimulants and more.

Nanoparticles
  • Silver, Copper, Selenium, Chromium, Calcium
Antibodies — IQNS™
  • IgY antibodies against Vibrio species (Immune Quantum Nano Sphere delivery)
Vitamins
  • A, D, E, K, B1, B2, B3, B5, B7, B9, B12, C
Chelated Minerals
  • Na, K, Ca, Mg, Mn, Fe, Co, Cr, B, Mo, Sn, Se, Ti, I, Ag, Cu, Ga, Cl

Composition — CQNS™-Doped Herbal Actives

CQNS™-Doped
Herbal Actives

CQNS™-doped — Herbal actives: Cinnamaldehyde, Citral A, Citral B, Carvacrol, terpinen-4-ol, Cymene, Curcumin, Turmerone, Andrographolide, Silymarin, d-terpineol, linalool, β-funebrene, β-elemene, spathulenol, a-pinene, b-pinene, myrcene, limonene, linalool, methyl chavicol, nerolidol, geranyl acetate, Allicin, Oleuropein, Lauric acid.

Terpenes
Carvacrol, terpinen-4-ol, Cymene, d-terpineol, linalool, a-pinene, b-pinene, myrcene, limonene.
Curcuminoids
Curcumin, Turmerone — potent anti-inflammatories and antimicrobials.
Other Actives
Andrographolide, Silymarin, β-funebrene, β-elemene, spathulenol, methyl chavicol, nerolidol, geranyl acetate, Allicin, Oleuropein, Lauric acid.

Composition — CQNS™-Doped Essential Oils

Essential Oils, Organic Acids
and Immunostimulants

A comprehensive blend of essential oils, organic acids, immunostimulants, phospholipids, amino acids, nucleic acids, natural binders and excipients.

CQNS™-Doped Essential Oils
  • Carvacrol, thyme oil, tea tree oil, cinnamon oil, curcumin oil, EPA, DHA, vegetable oil
Organic Acids
  • Lauric acid, butyric acid, propionic acid, acetic acid, citric acid
Immunostimulants
  • Beta glucan, yeast cell wall, fructooligosaccharides, mannooligosaccharides, vitamin E, selenium, k-carrageenan
Phospholipids
  • Soy lecithin, rapeseed lecithin, sunflower lecithin
Amino Acids
  • All 20 plant-derived amino acids
Nucleic Acids
  • Yeast nucleic acid
Natural Binders
  • Natural vegetable gums and resin
Excipients
  • Calcium carbonate

8. Feeding Program

Prevention
and Treatment Doses

The feeding program is designed to cover both routine prevention and active treatment in case of outbreaks, adapting to the needs of the culture cycle.

Recommended Dose

Alternate feeding — prevention and treatment.

Prevention
2.5 g
per kg of feed
Prevention
Alternate feeding from day 5 (DOC) to 45 days DOC.
Treatment
5 g
per kg of feed
Treatment
Alternate feeding for two weeks.

Mode of Use

01 — Weigh the dose: weigh 2.5 g (prevention) or 5 g (treatment) according to the indicated program.
02 — Dissolve in water: dissolve 2.5 g in 50 ml of water, or 5 g in 100 ml of water, before mixing with 1 kg of feed.
03 — Mix with feed: mix the prepared solution with 1 kg of feed evenly.
04 — Dry and supply: dry for 30 minutes before supplying to the pond.

9. Trial Results — Description

Performance in an
EHP-Infected Pond

Description: performance of VETRA STABIL AQ in an EHP-infected pond, compared across three pond conditions.

1

Pond 1

Negative control (uninfected pond).

2

Pond 2

Pond treated with VETRA STABIL AQ.

3

Pond 3

Positive control (untreated pond).

Parameter
Detail
Pond size
Approximately 1.5 acre
Age group
DOC 62
Study location
Ongole, AP
Time
April – May, 2018
Dose
5 grams/kg of feed for 14 days

10. Key Results & PCR

VETRA STABIL AQ Works
in EHP-Infected Animals

Reduced size variability of animals in the control tray and improved PCR results following treatment with VETRA STABIL AQ.

Key Results
1. Untreated ponds, found positive for EHP at the same location, showed stunted growth.

2. The pond treated with VETRA STABIL AQ showed no size variability and disease-free growth.

3. Feed consumption of the treated group improved and recovered body weight.

4. Treated animals were found free of WFS.
PCR Results & Observation
Infected animals — PCR data: positive for EHP, with size variability and stunted growth observed in untreated ponds.

Treated animals — PCR data: improvement in PCR results, reduced size variability and recovery of normal growth after treatment with VETRA STABIL AQ.

11. Producer Feedback

Feedback from Producers
Trialing VETRA STABIL AQ

Some comments from producers with VETRA STABIL AQ trials — consistently at 5 g/kg over 14 days.

Pond Symptom
Dosage
Days
General Response
Size variation, WFS
5 g/kg
14
Size variation problem resolved and increase in feed consumption, WFS cleared
WFS
5 g/kg
14
Works well, WFS cleared, satisfied, improvement in feed consumption
WFS, size variation
5 g/kg
14
WFS cleared, size variation improved, feed consumption improved
WFS
5 g/kg
14
WFS cleared, no size variation, feed consumption improved
WFS
5 g/kg
14
WFS gone, feed consumption improved
WFS, soft shell
5 g/kg
14
Fully satisfied, WFS was cleared, soft shell controlled, consumption improved
Soft shell, WFS
5 g/kg
14
No soft shell, WFS cleared, consumption improved
WFS, soft shell
5 g/kg
14
WFS controlled, no soft shell, feed consumption improved

12. Field Report

Context, Impact
and Analysis

A field report covering the context of the study, its economic impact and the profitability analysis for shrimp producers.

1. Context
Producers want to protect their ponds from EHP and vibriosis infections. Farm cost and income are evaluated with the prevention of losses due to stunted growth from microsporidiosis. The aim is to give the producer confidence to minimize the risk of financial losses from stunted growth and White Feces Syndrome.
2. Impact
The study provided the confidence that helped the producer evaluate the economic impacts of stunted-growth risk and losses that can be minimized with this therapy. It also identified the market opportunity that the product gives confidence for a disease-free culture to prevent vibriosis problems.
3. Analysis
Profitability is calculated based on how long the culture was maintained after preventive application of VETRA STABIL AQ. Harvest is the producer's sole decision; the research team calculated the risk assessment. Overall data show producers are free of stress from EHP, stunted growth and vibriosis.
Sustainable shrimp culture

Quantum Nanotechnology

"Disease-free culture and
consistent productivity."

Vetra Stabil AQ

"Preventive formulation for the control of EHP and vibriosis, growth improvement and consistent productivity in shrimp culture."

Contact the Technical Team