Q-Bervida
Controlled-release berberine that doesn't dump and disappear. Q-Bervida is a B2B delivery advance for premium metabolic-wellness formulations: berberine re-engineered with patent-pending PQNS Phytosome Quantum Nano Sphere, part of the QuanticSphere™ delivery platform, for a smooth, sustained in-vitro release instead of a first-hour burst.
“Berberine that doesn't burst and bail.”
~97% release over 8 hours — with no first-hour burst
USP conventional vs berberine-PQNS, N=1 lead formulation. Mean cumulative berberine release (%) vs time (h), USP conditions — lead formulation Sample E, fasting.
In-vitro dissolution data, N=1 lead formulation. Not intended to diagnose, treat, cure or prevent any disease.
Berberine is encapsulated in a Phytosome Quantum Nano Sphere
It shields the poorly-soluble active and releases it by diffusion — trading the first-hour burst for a smooth curve to ~97% over 8 hours. Kinetics are tunable to a target profile.
Encapsulation
Phospholipid nano-matrix shields the poorly-soluble active from the GI environment.
Tunable Kinetics
Release profile is tunable to a target window (lead formulation Sample E).
Diffusion Control
Releases by diffusion — a smooth, sustained curve instead of a first-hour spike.
Stability & Shelf Life
Robust, reproducible batch-to-batch performance for premium positioning.
Berberine that doesn't burst and bail
Berberine is encapsulated in a Phytosome Quantum Nano Sphere that shields the poorly-soluble active and releases it by diffusion — trading the first-hour burst for a smooth curve to ~97% over 8 hours. Kinetics are tunable to a target profile.
Robust, reproducible batch-to-batch performance for premium positioning.
Technical specification
Common questions about Q-Bervida
Straight answers for formulators, distributors and brand buyers.
Q-Bervida is a B2B delivery advance for premium metabolic-wellness formulations: berberine re-engineered with patent-pending PQNS (Phytosome Quantum Nano Sphere), part of the QuanticSphere™ delivery platform, for a smooth, sustained in-vitro release instead of a first-hour burst.
In USP dissolution testing, Q-Bervida released ~42% in the first hour and ~60% at 2 hours, reaching ~97% over 8 hours. Conventional berberine released ~90% in the first hour and ~95% at 2 hours — a first-hour burst instead of a sustained curve.
PQNS (Phytosome Quantum Nano Sphere) encapsulates berberine in a phospholipid nano-matrix that shields the poorly-soluble active from the GI environment and releases it by diffusion — trading the first-hour burst for a smooth curve to ~97% over 8 hours. Kinetics are tunable to a target profile, as demonstrated in lead formulation Sample E.
The PQNS vesicle size is 196.7 nm by DLS, with an 8-hour diffusion-controlled release. QuanticSphere™ — the PQNS technology — is patent pending (application 202521095813).
Yes. Q-Bervida is manufactured under GMP – 21 CFR 111, US DSHEA compliance, using a GRAS-compliant phospholipid carrier.
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