Q-Oxivia
Precision CoQ10 Delivery. Coenzyme Q10 delivered through QuanticSphere™ PQNS nanotechnology — 8.2× the systemic exposure of plain CoQ10 in a four-arm preclinical PK study.
Higher peak — and it stays up.
Higher peak — and it stays up
Mean plasma CoQ10 measured after a single oral dose, across four delivery forms.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Three reasons plain CoQ10 underperforms
Barely dissolves
863 Da, log P ≈ 11–13 — barely dissolves.
Falls with age
Depletes from around age 30.
Unpredictable
100–200 mg/day, uptake still erratic.
From 3.9 to 32.1 — the full four-arm comparison
Five mechanisms, one nano-sphere
PQNS is engineered to solve CoQ10's absorption problem at every step of gastrointestinal transit.
Nano-sizing
Transcellular transport across the gut wall, past dissolution limits.
Lymphatic routing
Channels lipophilic CoQ10 through lymphatics, avoiding first-pass loss.
Bile-salt solubilization
Keeps CoQ10 in an absorbable state through GI transit.
Mucoadhesion
Charged surface adheres to enterocytes, extending the window.
Efflux-pump evasion
Slips past P-gp efflux that pumps cargo back into the lumen.
What Q-Oxivia is formulated to support
Built for formulators
Common questions about Q-Oxivia
Straight answers for formulators, distributors and brand buyers.
Q-Oxivia is Coenzyme Q10 delivered through QuanticSphere™ PQNS nanotechnology — engineered for 8.2× the systemic exposure of plain CoQ10, measured in a four-arm preclinical PK study.
In the preclinical PK study, Q-Oxivia reached an AUC₀–₂₄ of 32.12 µg/mL·h versus 3.92 for plain CoQ10, 6.14 for CoQ10 + piperine and 10.71 for CoQ10 in jojoba oil — an 8.2× relative bioavailability gain. Peak plasma (Cmax) was 6.89 vs 2.24 µg/mL for plain CoQ10, and mean residence time was 10.3 h versus 6.3 h for plain CoQ10 (+65% t½).
PQNS (Phytosome Quantum Nano Sphere) works through five mechanisms: nano-sizing for transcellular transport across the gut wall; lymphatic routing that channels lipophilic CoQ10 through lymphatics, avoiding first-pass loss; bile-salt solubilization that keeps CoQ10 in an absorbable state through GI transit; mucoadhesion, where a charged surface adheres to enterocytes and extends the absorption window; and efflux-pump evasion, slipping past the P-gp efflux pump that would otherwise return cargo to the lumen.
Plain CoQ10 barely dissolves (863 Da, log P ≈ 11–13), the body's own CoQ10 depletes from around age 30, and dosing is unpredictable — at 100–200 mg/day, uptake is still erratic. PQNS is engineered to address solubility, delivery and consistency at once.
Request samples, MOQ and the full clinical dossier at info@integriacare.com.
Request samples, MOQ & the full clinical dossier
Talk to our team about volumes, blend specifications and technical documentation for your finished product.